Successful pregnancy outcome after in vitro fertilization in a pancreas-kidney recipient

Abstract

Objective: To describe the first case of IVF pregnancy in a pancreas-kidney recipient.

Design: Case report.

Setting: Reproductive Medicine Department, Hôpital Edouard Herriot, Lyon, France.

Intervention(s): In vitro fertilization in a pancreas-kidney recipient.

Patient(s): A 39 year-old nulliparous woman, with primary infertility and a history of pancreas-kidney transplant at 29 years of age.

Main outcome measure(s): Multidisciplinary agreement for the couple to be managed by IVF. Follow-up of pregnancy and delivery.

Result(s): Singleton IVF pregnancy in a pancreas-kidney recipient, maintained up to 34 weeks. Cesarian delivery ahead of labor. No severe maternal or fetal complications. Live birth. Normal postpartum renal function and glycemia.

Conclusion(s): An IVF pregnancy is feasible in a pancreas-kidney recipient. Such treatment should follow agreement by all the medical teams following the patient. Pregnancy in a pancreas-kidney recipient is at-risk, requiring close monitoring.