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. 2008 Feb;10(1):104-5.

doi: 10.1215/15228517-2007-043. Epub 2007 Nov 30.

Evaluation of glioma proliferation by 99mTc-Tetrofosmin

George A Alexiou¹, Spyridon Tsiouris, Ann Goussia, Athanasios Papadopoulos, Athanasios P Kyritsis, Konstantinos S Polyzoidis, Andreas D Fotopoulos

Affiliations

PMID: 18055861
PMCID: PMC2600831
DOI: 10.1215/15228517-2007-043

Evaluation of glioma proliferation by 99mTc-Tetrofosmin

George A Alexiou et al. Neuro Oncol. 2008 Feb.

. 2008 Feb;10(1):104-5.

doi: 10.1215/15228517-2007-043. Epub 2007 Nov 30.

Authors

George A Alexiou¹, Spyridon Tsiouris, Ann Goussia, Athanasios Papadopoulos, Athanasios P Kyritsis, Konstantinos S Polyzoidis, Andreas D Fotopoulos

Affiliation

¹ Department of Neurosurgery, University of Ioannina School of Medicine, Greece. alexiougrg@yahoo.gr

PMID: 18055861
PMCID: PMC2600831
DOI: 10.1215/15228517-2007-043

No abstract available

PubMed Disclaimer

Figures

Figure 1
T1-weighted, gadolinium-enchanced MRI (A) in a low-grade oligodendroglioma of the left frontal lobe. Faint ^99mTc-Tetrofosmin uptake (B, arrow) correlated with Ki-67 approx. 2% (C; MIB-1 ×100).

Figure 2
T1-weighted, gadolinium-enchanced MRI (A) in an anaplastic oligodendroglioma of the left temporal lobe. Profound tracer uptake (B) correlated with intense proliferation (C; Ki-67 approx. 40%, MIB-1 ×100).

Figure 3
Correlation between ^99mTc-Tetrofosmin uptake (expressed as lesion-to-normal [L/N] uptake ratio) and cellular proliferation rate (MIB-1) in the studied gliomas.

See this image and copyright information in PMC

Comment in

In Reference to Alexiou et al. (Neuro-Oncology 2008;10:104-105). Evaluation of glioma proliferation by 99mTc-Tetrofosmin.
Beauchesne P. Beauchesne P. Neuro Oncol. 2008 Aug;10(4):643. doi: 10.1215/15228517-2008-039. Epub 2008 Jun 24. Neuro Oncol. 2008. PMID: 18577563 Free PMC article. No abstract available.

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References

1. Quiñones-Hinojosa A, Sanai N, Smith JS, et al. Techniques to assess the proliferative potential of brain tumors. J Neurooncol. 2005;74:19–30. - PubMed

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