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Randomized Controlled Trial
. 2007 Dec 15;335(7632):1251-4.
doi: 10.1136/bmj.39399.456551.25. Epub 2007 Dec 4.

Hemiarthroplasty or internal fixation for intracapsular displaced femoral neck fractures: randomised controlled trial

Frede Frihagen  1 , Lars Nordsletten, Jan Erik Madsen
Affiliations
Randomized Controlled Trial

Hemiarthroplasty or internal fixation for intracapsular displaced femoral neck fractures: randomised controlled trial

Frede Frihagen et al. BMJ. .

Abstract

Objective: To compare the functional results after displaced fractures of the femoral neck treated with internal fixation or hemiarthroplasty.

Design: Randomised trial with blinding of assessments of functional results.

Setting: University hospital.

Participants: 222 patients; 165 (74%) women, mean age 83 years. Inclusion criteria were age above 60, ability to walk before the fracture, and no major hip pathology, regardless of cognitive function.

Interventions: Closed reduction and two parallel screws (112 patients) and bipolar cemented hemiarthroplasty (110 patients). Follow-up at 4, 12, and 24 months.

Main outcome measures: Hip function (Harris hip score), health related quality of life (Eq-5d), activities of daily living (Barthel index). In all cases high scores indicate better function.

Results: Mean Harris hip score in the hemiarthroplasty group was 8.2 points higher (95% confidence interval 2.8 to 13.5 points, P=0.003) at four months and 6.7 points (1.5 to 11.9 points, P=0.01) higher at 12 months. Mean Eq-5d index score at 24 months was 0.13 higher in the hemiarthroplasty group (0.01 to 0.25, P=0.03). The Eq-5d visual analogue scale was 8.7 points higher in the hemiarthroplasty group after 4 months (1.9 to 15.6, P=0.01). After 12 and 24 months the percentage scoring 95 or 100 on the Barthel index was higher in the hemiarthroplasty group (relative risk 0.67, 0.47 to 0.95, P=0.02. and 0.63, 0.42 to 0.94, P=0.02, respectively). Complications occurred in 56 (50%) patients in the internal fixation group and 16 (15%) in the hemiarthroplasty group (3.44, 2.11 to 5.60, P<0.001). In each group 39 patients (35%) died within 24 months (0.98, 0.69 to 1.40, P=0.92)

Conclusions: Hemiarthroplasty is associated with better functional outcome than internal fixation in treatment of displaced fractures of the femoral neck in elderly patients.

Trial registration: NCT00464230.

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Conflict of interest statement

Competing interests: FF has received lecture fees from OrtoMedic, who market orthopaedic implants; LN has received consulting and lecture fees from DePuy, Biomet, OrtoMedic, and SCP, who all manufacture and market orthopaedic implants.

Figures

None
Recruitment and flow of patients with intracapsular femoral neck fractures during study
See this image and copyright information in PMC

Comment in

References

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