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Review
. 2007;23(5-6):453-7.
doi: 10.1155/2007/674058.

Claudin proteins in ovarian cancer

Patrice J Morin  1
Affiliations
Review

Claudin proteins in ovarian cancer

Patrice J Morin. Dis Markers. 2007.

Abstract

Members of the claudin family of tight junction proteins have been found altered in several malignancies, including ovarian cancer. Because claudin-3 and -4 are elevated in the vast majority of ovarian tumors, they may represent useful biomarkers for detection and prognosis, as well as ideal targets for therapy using the Clostridium perfringens enterotoxin.

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