Review
[Parathyroid and bone. Bone metabolism in hypoparathyroidism]
[Article in
Japanese]
Affiliations
- PMID: 18057660
Item in Clipboard
Review
[Parathyroid and bone. Bone metabolism in hypoparathyroidism]
[Article in
Japanese]
Clin Calcium.
2007 Dec.
Abstract
Hypoparathyoidism is classified into two categories: PTH deficient and PTH refractory (i.e. pseudohypoparathyrodism [PHP]). Bone metabolism is different between the two. In PTH deficient hypoparathyroidism such as post-operative hypoparathyroidism, BMD is increased with relatively low bone turnover markers. In PHP, which characterized by PTH resistance in proximal renal tubules, bone response to PTH is sometimes preserved. In some PHP cases, high bone turnover state is observed, which correlates with serum PTH levels.
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