Response to Mycobacterium tuberculosis antigens is enhanced by monoclonal antibodies
- PMID: 1805883
Response to Mycobacterium tuberculosis antigens is enhanced by monoclonal antibodies
Abstract
T lymphocytes purified from peripheral blood of tuberculosis patients and from healthy skin test PPD-positive subjects show a remarkably increased proliferative response in culture to purified protein derivative (PPD) when three anti-mycobacterial monoclonal antibodies are added together with the antigen. This indicates an important role played by antibodies in the T cell response to the tuberculous infection.
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