doi: 10.1016/0025-5564(91)90016-c.
Analyzing effects of vaccines
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- PMID: 1806125
- DOI: 10.1016/0025-5564(91)90016-c
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Analyzing effects of vaccines
Math Biosci.
1991 Dec.
Abstract
A population with (individually) varying susceptibilities to infection and a vaccine with (individually) varying protective effect are considered. A simple stochastic model is used to illustrate different effects of the vaccine on the spread of the infection. The behavior of different estimators of the vaccine efficacy using data from a clinical trial and the relation between vaccine efficacy and the effectiveness of a vaccination program are discussed.
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