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Review
. 2007 Nov-Dec;9(14-15):1636-43.
doi: 10.1016/j.micinf.2007.09.010. Epub 2007 Sep 14.

The Mx GTPase family of interferon-induced antiviral proteins

Otto Haller  1 , Silke Stertz, Georg Kochs
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Free article
Review

The Mx GTPase family of interferon-induced antiviral proteins

Otto Haller et al. Microbes Infect. 2007 Nov-Dec.
Free article

Abstract

Mx proteins are interferon-induced members of the dynamin superfamily of large GTPases. They inhibit a wide range of viruses by blocking an early stage of the replication cycle. Studies in genetically defined mouse strains highlight their powerful action in early antiviral host defence.

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