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. 2008 Mar 1;16(5):2403-11.
doi: 10.1016/j.bmc.2007.11.054. Epub 2007 Nov 28.

Synthesis and structure-immunosuppressive activity relationships of bakuchiol and its derivatives

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Synthesis and structure-immunosuppressive activity relationships of bakuchiol and its derivatives

Hongli Chen et al. Bioorg Med Chem. .

Abstract

A series of derivatives of bakuchiol were synthesized and tested in vitro for their cytotoxicity, and inhibition of T cell proliferation and B cell proliferation. The data obtained provided preliminary structure-activity relationships of the compounds as immunosuppressive activity.

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