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. 2008 Jan;46(1):357-60.
doi: 10.1128/JCM.01593-07. Epub 2007 Dec 6.

Rare AU-1-like G3P[9] human rotaviruses with a Kun-like NSP4 gene detected in children with diarrhea in Italy

S De Grazia  1 , G M Giammanco, V Martella, S Ramirez, C Colomba, A Cascio, S Arista
Affiliations

Rare AU-1-like G3P[9] human rotaviruses with a Kun-like NSP4 gene detected in children with diarrhea in Italy

S De Grazia et al. J Clin Microbiol. 2008 Jan.

Abstract

Three G3P[9] rotaviruses, detected in children hospitalized with gastroenteritis in Palermo, Italy, were found to be genetically related to strains of either human or feline origin in the VP7, VP4, and VP6 genes. In contrast, in the NSP4 gene the viruses resembled G2P[4] human strains, suggesting a reassortment between AU-1-like and Kun-like strains.

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Figures

FIG. 1.
FIG. 1.
Phylogenetic analysis of deduced amino acid sequence of the VP7 (a), VP4 (b), VP6 (c), and NSP4 (d) genes. The phylogeny was inferred by the neighbor-joining method and by use of the Kimura two-parameter model as the method of substitution. The statistical significance was estimated by bootstrap analysis with 1,000 pseudoreplicate data sets. The origins of the rotavirus strains are indicated as follows: hu, human; fe, feline; ca, canine; eq, equine; si, simian; la, lapine; bo, bovine; po, porcine; mu, murine; and av, avian. In panel a, strains with atypical positions in the VP7 tree are highlighted in boldface.
See this image and copyright information in PMC

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