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Review
. 2007 Dec:157 Suppl 2:32-3.
doi: 10.1111/j.1365-2133.2007.08270.x.

Update on actinic keratosis in clinical trial experience with imiquimod

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Review

Update on actinic keratosis in clinical trial experience with imiquimod

C Ferrándiz. Br J Dermatol. 2007 Dec.

Abstract

Actinic keratoses (AK) is a sun induced cutaneous lesion, currently considered as a squamous cell carcinoma in situ that has the potential to progress to invasive SCC. To treat them, numerous, ablative and no ablative, therapeutic approaches exist. Among them, imiquimod, a toll like receptor agonist, recently approved to treat them in the US and Europe, has demonstrated to be effective and safe with an acceptable tolerability in the treatment of these lesions. In this article the results of several high quality RCT are analysed.

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