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Review
. 2008 Feb;19(1):33-40.
doi: 10.1016/j.cytogfr.2007.10.007.

Type I interferon as a stimulus for cross-priming

Agnès Le Bon  1 , David F Tough
Affiliations
Review

Type I interferon as a stimulus for cross-priming

Agnès Le Bon et al. Cytokine Growth Factor Rev. 2008 Feb.

Abstract

Type I interferon (IFN-alpha/beta) is induced rapidly by infection and is well recognised for its crucial role in innate defence. However, it is evident that IFN-alpha/beta also serves as a signal for the generation of adaptive immune responses. In this review, we focus on the involvement of IFN-alpha/beta in the induction of CD8+ T cell responses by cross-priming.

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