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. 2006 Sep;2(3):108-11.
doi: 10.1007/BF03161019.

Phentolamine therapy for cocaine-association acute coronary syndrome (CAACS)

Gar Ming Chan  1 , Rahul Sharma, Dennis Price, Robert S Hoffman, Lewis S Nelson
Affiliations

Phentolamine therapy for cocaine-association acute coronary syndrome (CAACS)

Gar Ming Chan et al. J Med Toxicol. 2006 Sep.

Abstract

Introduction: The emergency department (ED) evaluation of cocaine-associated acute coronary syndrome (CAACS) is often a diagnostic and therapeutic challenge.

Case report: We are reporting on the treatment of a patient with cocaine-associated acute coronary syndrome (CAACS) who did not benefit from standard therapy, but who eventually responded positively to phentolamine, an alpha-adrenergic receptor antagonist.

Discussion: This report should encourage physicians to add phentolamine to their pharmacotherapeutic armamentarium in the treatment of CAACS.

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