Diagnostic challenges in extrauterine epithelioid trophoblastic tumours: a report of two cases

Abstract

Introduction: Epithelioid trophoblastic tumour (ETT) is a rare condition with a paucity of cases reported in the literature.

Case reports: We present two unusual cases of ETT. Both patients presented with markedly elevated hCG levels; one case presented with a mass in the gallbladder, the other with extensive metastases; and both patients died from disease.

Discussion: To gain a greater understanding of the nature and progression of this disease, reporting of cases in the literature should be thorough and contain detailed information on patient clinicopathological characteristics and treatment. To enable identification of prognostic factors, long-term follow up must also be reported because recurrence can be both late and complex.