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. 2008 Jan;9(1):22-6.
doi: 10.1038/sj.embor.7401140. Epub 2007 Dec 14.

Reining in RNA. Workshop on intracellular RNA localization and localized translation

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Reining in RNA. Workshop on intracellular RNA localization and localized translation

Patrick C Gilligan et al. EMBO Rep. 2008 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Ribbon representation of the Sulfolobus solfataricus exosome including a Corey–Pauling–Koltun model of the RNA bound in the structure. A possible path for RNA substrates is indicated by a magenta-coloured line. In this model, the 3′ end of the RNA substrate is recruited by the S1 pore and threaded through the neck of the central channel to the processing chamber, where it binds at one of the active sites and is degraded in a processive manner. (Figure reproduced with permission from Lorentzen et al, 2007).
Figure 2
Figure 2
Potential use of a dual-visualization system in live fly egg chambers. In the hypothetical example, posterior localization of oskar RNA tagged with λN/BoxB is visualized with an amino-peptide:red fluorescent protein (RFP) fusion; gurken RNA, localized later to dorsal, is tagged with MS2 hairpins and visualized with a MS2CP:green fluorescent protein (GFP) fusion protein.
None
Patrick C. Gilligan
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Karuna Sampath
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The first joint EMBO/FASEB Workshop on Intracellular RNA Localization and Localized Translation took place between 1 and 6 July 2007, in Il Ciocco, Italy, and was organized by A. Ephrussi, E. Gavis, D. Ish-Horowicz and J. Richter. Originally a biannual FASEB summer research conference, it is anticipated that the joint meeting will in future alternate between sites in Europe and the USA.

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