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. 2007 Nov-Dec;15(6):429-34.
doi: 10.1080/09273940701798546.

An epidemic of chronic pseudophakic endophthalmitis due to Ochrobactrum anthropi: clinical findings and managements of nine consecutive cases

Seung Song  1 , Jae Kyoun Ahn, Gwang Hoon Lee, Yeoung Geol Park
Affiliations

An epidemic of chronic pseudophakic endophthalmitis due to Ochrobactrum anthropi: clinical findings and managements of nine consecutive cases

Seung Song et al. Ocul Immunol Inflamm. 2007 Nov-Dec.

Abstract

Purpose: To report an epidemic of O. anthropi pseudophakic endophthalmitis.

Methods: The medical records of nine patients with culture-proven O. anthropi endophthalmitis were reviewed.

Results: The presenting features were compatible to chronic endophthalmitis. Two patients showed coinfections with P. acnes. Antibiotics sensitivity test revealed susceptibility to quinolones. Pars plana vitrectomy (PPV) with partial capsulectomy (PC) cured infections in seven patients without coinfection of P. acnes. Final visual acuity was 20/40 or better in five patients.

Conclusions: O. anthropi should be considered in cases with chronic pseudophakic endophthalmitis. PPV with PC should be the initial therapeutic option for O. anthropi endophthalmitis.

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Figures

FIGURE 1
FIGURE 1
Time interval between cataract surgery and initial treatment of each patient.
FIGURE 2
FIGURE 2
Representative anterior segment photograph of O. anthropi endophthalmitis. The photograph shows hypopyon, corneal edema, intraocular fibrin, and capsular white materials.
FIGURE 3
FIGURE 3
Electron microscopic findings of explanted intraocular lens (IOL) and residual capsule in two patients with coinfection of O. anthropi and P. acnes. (A) Scanning electron microscopy of a patient (No. 9) reveals polymorphic and rod-shaped bacillus at the surface of explanted IOL. (B) Transmission electron microscopy of a patient (No. 8) also shows the polymorphic organisms with diverse sizes (arrowhead) and a pathogen-laden macrophage (arrow).
See this image and copyright information in PMC

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