[Neuropathy, monoclonal gammopathy and autoantibodies: how to establish a link?]

Abstract

Monoclonal gammopathies are frequently observed in subjects older than 50 years. Understanding the pathogenetic role of paraproteins in peripheral nervous system damage is a necessary step to establish a link between the monoclonal gammopathy and neuropathy. The clinical, electrophysiological, biological and histopathological features of these neuropathies related to paraproteins are important to ensure appropriate treatments.