Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Apr;27(4):515-6.
doi: 10.1007/s10067-007-0810-z. Epub 2007 Dec 18.

Anticitrulline peptide antibodies (CCP3) in leprosy sera: a negative association

Luiz Sergio Guedes-Barbosa  1 , Cristovão Mangueira, Morton Scheinberg
Affiliations

Anticitrulline peptide antibodies (CCP3) in leprosy sera: a negative association

Luiz Sergio Guedes-Barbosa et al. Clin Rheumatol. 2008 Apr.

Abstract

Anticyclic citrullinated peptide antibodies (anti-CCP) have been described almost exclusively in patients with rheumatoid arthritis. Recently, these autoantibodies have been found in patients with active tuberculosis. Leprosy is another mycobacterial disease where the presence of autoantibodies has been described by several authors. In this study, 64 patients with leprosy (32 paucibacillary and 32 multibacillary forms of the disease) were evaluated and only 2 patients were positive for the presence of anti-CCP. The low frequency of anti-CCP in leprosy sera demonstrated in our study illustrates the high specificity of anti-CCP for the diagnosis of rheumatoid arthritis.

PubMed Disclaimer

Comment in

References

    1. Clin Rheumatol. 1996 Jan;15(1):26-8 - PubMed
    1. QJM. 2007 Apr;100(4):193-201 - PubMed
    1. Arthritis Rheum. 2003 Oct;48(10):2741-9 - PubMed
    1. Clin Rheumatol. 2007 Feb;26(2):208-10 - PubMed
    1. Ann Rheum Dis. 2006 Aug;65(8):1110-2 - PubMed

LinkOut - more resources