Review
doi: 10.1016/j.coms.2007.07.004.
Bone morphogenetic proteins: a realistic alternative to bone grafting for alveolar reconstruction
Affiliations
- PMID: 18088904
- DOI: 10.1016/j.coms.2007.07.004
Item in Clipboard
Review
Bone morphogenetic proteins: a realistic alternative to bone grafting for alveolar reconstruction
Oral Maxillofac Surg Clin North Am.
2007 Nov.
Abstract
Preclinical studies have shown that rhBMP-2 induces normal physiologic bone in clinically relevant defects in the craniofacial skeleton. The newly formed bone assumes characteristics of the adjacent resident bone and allows placement, osseointegration/re-osseointegration, and functional loading of endosseous implants. Clinical studies optimizing dose, delivery technologies, and conditions for stimulation of bone growth will bring about a new era in dentistry. The ability to predictably promote osteogenesis through the use of bone morphogenetic protein technologies is not far from becoming a clinical reality and will have an astounding effect on how dentistry is practiced.
Similar articles
-
Bone morphogenetic proteins for periodontal and alveolar indications; biological observations - clinical implications.Orthod Craniofac Res. 2009 Aug;12(3):263-70. doi: 10.1111/j.1601-6343.2009.01461.x. Orthod Craniofac Res. 2009. PMID: 19627529 Review.
-
Bone formation and osseointegration stimulated by rhBMP-2 following subantral augmentation procedures in nonhuman primates.Int J Oral Maxillofac Implants. 1997 Nov-Dec;12(6):785-92. Int J Oral Maxillofac Implants. 1997. PMID: 9425759
-
Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: histologic observations.J Clin Periodontol. 2008 Nov;35(11):1001-10. doi: 10.1111/j.1600-051X.2008.01321.x. J Clin Periodontol. 2008. PMID: 18976397
-
Alveolar ridge augmentation with rhBMP-2 and bone-to-implant contact in induced bone.Int J Periodontics Restorative Dent. 2001 Oct;21(5):461-73. Int J Periodontics Restorative Dent. 2001. PMID: 11693239
-
Tissue engineering with recombinant human bone morphogenetic protein-2 for alveolar augmentation and oral implant osseointegration: experimental observations and clinical perspectives.Clin Implant Dent Relat Res. 2005;7(2):112-9. doi: 10.1111/j.1708-8208.2005.tb00054.x. Clin Implant Dent Relat Res. 2005. PMID: 15996358 Review.
Cited by
-
Effects of block bone substitutes loaded with Escherichia Coli-produced recombinant human bone morphogenetic protein-2 on space maintenance and bone formation in rat calvarial onlay model.Tissue Eng Regen Med. 2016 Jun 9;13(3):311-321. doi: 10.1007/s13770-016-0011-4. eCollection 2016 Jun. Tissue Eng Regen Med. 2016. PMID: 30603413 Free PMC article.
-
Regeneration of periodontal ligament fibers around mini dental implants and their attachment to the bone in an animal model: A radiographic and histological study.J Indian Soc Periodontol. 2023 Mar-Apr;27(2):167-173. doi: 10.4103/jisp.jisp_314_22. Epub 2023 Mar 4. J Indian Soc Periodontol. 2023. PMID: 37152460 Free PMC article.
-
Effectiveness of Autologous Platelet Concentrates in the Sinus Lift Surgery: Findings from Systematic Reviews and Meta-Analyses.Dent J (Basel). 2024 Apr 10;12(4):101. doi: 10.3390/dj12040101. Dent J (Basel). 2024. PMID: 38668013 Free PMC article. Review.
-
Application of Recombinant Human BMP-2 with Bone Marrow Aspirate Concentrate and Platelet-Rich Fibrin in Titanium Mesh for Vertical Maxillary Defect Reconstruction prior to Implant Placement.Case Rep Dent. 2021 Oct 7;2021:6691022. doi: 10.1155/2021/6691022. eCollection 2021. Case Rep Dent. 2021. PMID: 34659842 Free PMC article.
-
An oligodeoxynucleotide with promising modulation activity for the proliferation and activation of osteoblast.Int J Mol Sci. 2011;12(4):2543-55. doi: 10.3390/ijms12042543. Epub 2011 Apr 15. Int J Mol Sci. 2011. PMID: 21731457 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
