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Comment
. 2007 Dec;27(6):825-7.
doi: 10.1016/j.immuni.2007.11.010.

MicroRNA-155 function in B Cells

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Free article
Comment

MicroRNA-155 function in B Cells

Kathryn Calame. Immunity. 2007 Dec.
Free article

Abstract

Vigorito et al. (2007) report (in this issue of Immunity) that B cells require microRNA (miR)-155 for normal production of isotype-switched, high-affinity antibodies and for a memory response. They identify transcriptional regulator Pu.1 as a functionally important target of miR-155 in B cells.

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