E proteins enforce security checkpoints in the thymus
- PMID: 18093534
- DOI: 10.1016/j.immuni.2007.12.001
E proteins enforce security checkpoints in the thymus
Abstract
In this issue of Immunity, two studies define new roles for E proteins in thymocyte development. Agata et al. (2007) show a new role in beta selection; Jones and Zhuang (2007) demonstrate a role in positive selection.
Comment on
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Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47.Immunity. 2007 Dec;27(6):871-84. doi: 10.1016/j.immuni.2007.11.015. Immunity. 2007. PMID: 18093539
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