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Case Reports
. 2007 Sep 6;125(5):295-6.
doi: 10.1590/s1516-31802007000500010.

Laryngeal adenoid cystic carcinoma: case report

André Del Negro  1 , Edson Ichihara, Alfio José Tincani, Albina Altemani, Antônio Santos Martins
Affiliations
Case Reports

Laryngeal adenoid cystic carcinoma: case report

André Del Negro et al. Sao Paulo Med J. .

Abstract
in English, Portuguese

Context: Adenoid cystic carcinomas are malignant tumors that occur in both the major and the minor salivary glands. A laryngeal location is rare because of the paucity of accessory salivary glands in this area. Adenoid cystic carcinomas account for less than 1% of all malignant tumors in the larynx, and only about 120 cases have been reported in the literature. These tumors have a slight female predisposition, and their peak incidence is in the fifth and sixth decades of life. In this article, we describe a case of laryngeal adenoid cystic carcinoma and discuss its clinical characteristics and treatment.

Case report: We report on a case of laryngeal adenoid cystic carcinoma in a 55 year-old female patient who presented with dyspnea and hoarseness. Features of the diagnostic and therapeutic evaluation are described and the clinical management of such cases is outlined. The clinical course, definitive treatment strategy and surgical procedure, and also adjuvant treatment with irradiation are discussed. Although the tumor is radiosensitive, it is not radiocurable.

CONTEXTO:: Carcinoma adenóide cístico (CAC) é um tumor maligno que ocorre tanto nas glândulas salivares maiores quanto nas menores. Localização laríngea é rara devido à paucidade de glândulas salivares acessórias nesta região. O carcinoma adenóide cístico representa menos de 1% das lesões malignas da laringe e apenas 120 casos foram relatados na literatura. O CAC tem freqüência discretamente superior no sexo feminino e seu pico de incidência ocorre entre a quinta e sexta décadas de vida. Neste artigo, descrevemos um caso de CAC laríngeo e discutimos suas características clínicas e seu tratamento.

RELATO DE CASO:: Relatamos o caso de CAC numa paciente de 55 anos que apresentava disfonia e dispnéia. Características diagnósticas e avaliação terapêutica são descritas e a conduta clínica definida. Evolução clínica, estratégia terapêutica e procedimento cirúrgico são discutidos, bem como o tratamento adjuvante com radioterapia. O tumor, apesar de radiossensível, não é radiocurável.

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Conflict of interest statement

Conflict of interest: None

Figures

Figure 1
Figure 1. Histological section of laryngeal adenoid cystic carcinoma. (400 x magnification and hematoxylineosin staining).
See this image and copyright information in PMC

References

    1. Javadi M, Bafrouee FM, Mohseni M, Asghari A. Laryngeal adenoid cystic carcinoma in a child: a case report. Ear Nose Throat J. 2002;81(1):34–35. - PubMed
    1. Morais Pérez D, Cortejoso Hernández A, Borau Clavero M, Martín Sigüenza G. Carcinoma adenoide quístico de laringe. [Adenoid cystic carcinoma of the larynx] Acta Otorrinolaringol Esp. 1999;50(8):660–663. - PubMed
    1. Dexemble P, Huth J, Rebufy M, Chabrol A. Carcinome adénoïde kystique du larynx. A propos de deux cas. [Cystic adenoid carcinoma of the larynx: two cases] Ann Otolaryngol Chir Cervicofac. 2003;120(4):244–248. - PubMed
    1. Tincani AJ, Del Negro A, Araújo PP, et al. Management of salivary gland adenoid cystic carcinoma: institutional experience of a case series. Sao Paulo Med J. 2006;124(1):26–30. - PMC - PubMed
    1. Kufeld M, Junker K, Sudhoff H, Dazert S. Kollisionstumor eines adenoidzystischen Karzinoms des Hypopharynx und eines Plattenepithelkarzinoms des Larynx. [Collision tumor of a hypopharyngeal adenoidcystic carcinoma and a laryngeal squamous cell carcinoma] Laryngorhinootologie. 2004;83(1):51–54. - PubMed

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