Comment
doi: 10.1016/j.chembiol.2007.12.003.
Fatty pain cures
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- PMID: 18096498
- DOI: 10.1016/j.chembiol.2007.12.003
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Comment
Fatty pain cures
Chem Biol.
2007 Dec.
Abstract
In this issue, Alvin King, Daniele Piomelli, and colleagues publish another interesting paper on inhibition of monoacylglycerol lipase (MGL). MGL is a hot target for antinociceptive agents, being the chief degrading enzyme of the endocannabinoid 2-arachidonoylglycerol.
Comment on
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URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.Chem Biol. 2007 Dec;14(12):1357-65. doi: 10.1016/j.chembiol.2007.10.017. Chem Biol. 2007. PMID: 18096504 Free PMC article.
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