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Case Reports
. 1991 Nov;13(6):457-8.
doi: 10.1016/s0387-7604(12)80050-7.

Characteristic changes on brain CT in a case of Leigh encephalopathy with deficiency of pyruvate dehydrogenase

Y Arai  1 , Y Miyasato, H Koide
Affiliations
Case Reports

Characteristic changes on brain CT in a case of Leigh encephalopathy with deficiency of pyruvate dehydrogenase

Y Arai et al. Brain Dev. 1991 Nov.

Abstract

A girl aged 23 months of Leigh encephalopathy with pyruvate dehydrogenase complex (PDHC) deficiency was reported. Brain CT scan showed atrophy of the frontal and parietal cortex, low density in the midbrain and putamina, and rounded caudatum. CT change was showed from rounded to atrophic caudatum during a three-month period. The rounded caudatum may be an early CT finding in Leigh encephalopathy.

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