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. 1976 Jun;33(6):626-33.
doi: 10.1038/bjc.1976.100.

Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice

I Muranyi-Kovacs, G Rudali, J Imbert
Free PMC article

Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice

I Muranyi-Kovacs et al. Br J Cancer. 1976 Jun.
Free PMC article

Abstract

Adult mice of strains C3Hf and XVII/G received 2, 4, 5-T by continuous oral administration (80 ppm in the diet). The 2, 4, 5-T preparation contained less than 0-05 ppm of dioxins. In 2, 4, 5-T -treated C3Hf mice a significant increase in the incidence of neoplastic lesions was found. No significant difference was found in the XVII/G strain between the treated and control mice. Rare forms of tumours, which were not observed in the controls, were present in the 2, 4, 5-t -treated C3Hf mice.

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