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. 1949 Apr 1;89(4):439-50.
doi: 10.1084/jem.89.4.439.

A type-specific protein from pneumococcus

R AUSTRIAN, C M MacLEOD

A type-specific protein from pneumococcus

R AUSTRIAN et al. J Exp Med. .

Abstract

The isolation and characterization of a type-specific M protein from pneumococcus are described. This protein is similar chemically in all respects studied to the M proteins of group A streptococci. No immunological crossreactions have been observed, however, between M proteins of the two species. Strains of capsular type I pneumococcus have been encountered which contain different M proteins. The same is true for capsular type II pneumococcus. It is apparent, therefore, that the capsular polysaccharides and M proteins can vary independently of each other.

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