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Case Reports
. 1991;17(1-2):116-20.
doi: 10.1159/000457507.

Chloral hydrate toxicity in a term infant

M A Anyebuno  1 , C R Rosenfeld
Affiliations
Case Reports

Chloral hydrate toxicity in a term infant

M A Anyebuno et al. Dev Pharmacol Ther. 1991.

Abstract

Chlorate hydrate is commonly used for neonatal sedation, but blood levels are infrequently monitored, reflecting an underemphasis of acute toxic effects. This report describes a case of chloral hydrate toxicity in a term infant with cardiac, renal, neurologic, bladder and gastrointestinal dysfunction. The effects of exchange transfusion are described as well as pharmacokinetics.

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