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. 1949 May;89(5):479-89.
doi: 10.1084/jem.89.5.479.

The effect of lithium periodate on crystalline bovine serum albumin

W F GOEBEL, G E PERLMANN

The effect of lithium periodate on crystalline bovine serum albumin

W F GOEBEL et al. J Exp Med. 1949 May.

Abstract

A study of the chemical, physicochemical, and immunological changes in bovine serum albumin, brought about by oxidation with lithium periodate, has been made. It has been shown that destruction of certain amino acids occurs, that a change in the absorption spectrum takes place, and that the electrophoretic behavior of the protein is altered. Prolonged contact of bovine albumin with lithium periodate destroys its ability to incite antibodies in experimental animals.

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References

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