Ribosomal frameshifting, jumping and readthrough
- PMID: 1814364
- PMCID: PMC7134649
- DOI: 10.1016/0955-0674(91)90128-l
Ribosomal frameshifting, jumping and readthrough
Abstract
New examples of high-level ribosomal frameshift and readthrough events have been described over the past year and a half. These include -1 frameshifting at tandem codons and +1 frameshifting at neighboring slow codons. Several bizarre examples of ribosome jumping and multiple stop-codon readthrough continue to perplex investigators in this field.
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References
-
- Weiss R.B., Dunn D.M., Shuh M., Atkins J.F., Gesteland R.F. E. coli Ribosomes Re-phase on Retroviral Frameshift Signals at Rates Ranging from 2 to 50 Percent. New Biol. 1989;1:159–169. - PubMed
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