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Review
. 2008 Jan:14 Suppl 1:63-74.
doi: 10.1111/j.1469-0691.2007.01863.x.

Extended-spectrum beta-lactamases: structure and kinetic mechanism

M G P Page  1
Affiliations
Free article
Review

Extended-spectrum beta-lactamases: structure and kinetic mechanism

M G P Page. Clin Microbiol Infect. 2008 Jan.
Free article

Erratum in

  • Clin Microbiol Infect. 2008 May;14 Suppl 5:21-4

Abstract

Recent years have seen an explosion in the numbers of extented spectrum class A beta-lactamases (ESBLs). The steady-state kinetic parameters for hydrolysis of beta-lactams by ESBLs is discussed in the light of what is known about the structure of these mutant enzymes.

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