Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2003 Mar;14(2):123-5.
doi: 10.1155/2003/675159.

Cepacia-like syndrome caused by Burkholderia multivorans

George Zahariadis  1 , Michelle H Levy, Jane L Burns
Affiliations
Case Reports

Cepacia-like syndrome caused by Burkholderia multivorans

George Zahariadis et al. Can J Infect Dis. 2003 Mar.

Abstract

The variable severity of Burkholderia cepacia complex infections in cystic fibrosis (CF) has recently been ascribed to differences in the virulence between genomovars. Specifically, genomovar III isolates have been associated with higher transmission rates and adverse outcomes compared to other B cepacia genomovars, and consequently further segregation between genomovar III and non-genomovar III B cepacia infected patients is advocated in some centres. The important role of non-genomovar III isolates is presented in the context of a clinical case whereby a patient with long-standing pulmonary infection with B multiovorans developed bacteremic infection reminiscent of the fatal 'cepacia syndrome'.

Keywords: Burkholderia; Cepacia syndrome; Cystic fibrosis; Genomovar.

PubMed Disclaimer

References

    1. Govan JRW, Hughes JE, Vandamme P. Burkholderia cepacia: medical, taxonomic and ecological issues. J Med Microbiol 1996;45:395-407. - PubMed
    1. Coenye T, Mahenthiralingam E, Henry D, et al. Burkholderia ambifaria: a novel member of the Burkholderia cepacia complex including biocontrol and cystic fibrosis-related isolates. Int J Syst Evol Microbiol 2001;51:1481-90. - PubMed
    1. Dailey RH, Benner EJ. Necrotizing pneumonitis due to the pseudomonal "eugonic oxidizer group 1". N Engl J Med 1968;279:361-2. - PubMed
    1. Isles A, Maclusky I, Corey M, et al. H. Pseudomonas cepacia infection in cystic fibrosis: an emerging problem. J Pediatr 1984;104:206-10. - PubMed
    1. Kaitwatcharachai C, Silpapojakul K, Jitsurong S, Kalnauwakul S. An outbreak of Burkholderia cepacia bacteremia in hemodialysis patients: an epidemiologic and molecular study. Am J Kidney Dis 2000;36:199-204. - PubMed

Publication types

LinkOut - more resources