Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Jul;19(1):279-85.
doi: 10.1128/JVI.19.1.279-285.1976.

Excision of viral DNA from host cell DNA after induction of simian virus 40-transformed hamster cells

T Rakusanova, J C Kaplan, W P Smales, P H Black

Excision of viral DNA from host cell DNA after induction of simian virus 40-transformed hamster cells

T Rakusanova et al. J Virol. 1976 Jul.

Abstract

Simian virus 40-transformed hamster cells were induced to produce infectious virus by treatment with mitomycin C or gamma-irradiation. A portion of the simian virus-40 DNA, which is integrated into the host cell genome in uninduced cells, was recovered in a pool of relatively low-molecular-weight DNA early after induction treatment in the absence of DNA replication. The data indicte that excision of the viral genome occurs subsequent to the induction stimulus.

PubMed Disclaimer

References

    1. Virology. 1975 Nov;68(1):215-20 - PubMed
    1. J Mol Biol. 1967 Jun 14;26(2):365-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1968 Aug;60(4):1288-95 - PubMed
    1. Annu Rev Microbiol. 1968;22:391-426 - PubMed
    1. J Mol Biol. 1971 Apr 14;57(1):129-45 - PubMed

Publication types

LinkOut - more resources