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. 2009 Mar;91(3):960-2.
doi: 10.1016/j.fertnstert.2007.08.061. Epub 2007 Dec 27.

Influence of polymorphism of glutathione S-transferase T1 on Chinese infertile patients with varicocele

Qifei Wu  1 , Junping Xing, Wei Xue, Jianhua Sun, Xinyang Wang, Xiaojuan Jin
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Free article

Influence of polymorphism of glutathione S-transferase T1 on Chinese infertile patients with varicocele

Qifei Wu et al. Fertil Steril. 2009 Mar.
Free article

Abstract

To investigate the influence of glutathione S-transferase T1 (GSTT1) gene polymorphism on Chinese infertile patients with varicocele, 63 infertile patients with varicocele and 54 healthy fertile controls were recruited in this case-control study. Our results show that oxidative damage may be the cause of infertility in patients with varicocele, and GSTT1 null genotype predisposes to over oxidative damage to spermatocytes of infertile patients with varicocele.

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