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Case Reports
. 2007 Dec;35(9):871-3.
doi: 10.1111/j.1442-9071.2007.01609.x.

Favourable response to infliximab in a case of bilateral refractory Mooren's ulcer

Luigi Fontana, Gabriella Parente, Piergiorgio Neri, Massimo Reta, Giorgio Tassinari
Case Reports

Favourable response to infliximab in a case of bilateral refractory Mooren's ulcer

Luigi Fontana et al. Clin Exp Ophthalmol. 2007 Dec.

Abstract

A woman with progressive bilateral Mooren's ulcer developed recurrent corneal perforations and melting requiring tectonic grafts, despite conventional immunosuppressant therapy. Following treatment with infliximab, an anti-tumour necrosis factor agent, the patient showed marked reduction in conjunctival inflammation and no further recurrence of corneal thinning and perforation during 2-year follow up on maintaining treatment.

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