Listen to the data when results are not significant

doi:10.1136/bmj.39379.359560.AD

. 2008 Jan 5;336(7634):23-5.

doi: 10.1136/bmj.39379.359560.AD.

Listen to the data when results are not significant

Catherine E Hewitt¹, Natasha Mitchell, David J Torgerson

Affiliations

PMID: 18174597
PMCID: PMC2174757
DOI: 10.1136/bmj.39379.359560.AD

Listen to the data when results are not significant

Catherine E Hewitt et al. BMJ. 2008.

. 2008 Jan 5;336(7634):23-5.

doi: 10.1136/bmj.39379.359560.AD.

Authors

Catherine E Hewitt¹, Natasha Mitchell, David J Torgerson

Affiliation

¹ York Trials Unit, Department of Health Sciences, University of York, York YO10 5DD.

PMID: 18174597
PMCID: PMC2174757
DOI: 10.1136/bmj.39379.359560.AD

Abstract

Unexpected non-significant results from randomised trials can be difficult to accept. Catherine Hewitt, Natasha Mitchell, and David Torgerson find that some authors continue to support interventions despite evidence that they might be harmful

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Conflict of interest statement

Competing interests None declared.

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References

1. Kaptchuk TJ. Effect of interpretive bias on research evidence. BMJ 2003;326:1453-5. - PMC - PubMed
1. Meyer G, Warnke A, Bender R, Muhlhauser I. Effect on hip fractures of increased use of hip protectors in nursing homes: cluster randomised controlled trial. BMJ 2003;326:76-80. - PMC - PubMed
1. Craig TKJ, Garety P, Power P, Rahaman N, Colbert S, Fornells-Ambrojo M, et al. The Lambeth Early Onset (LEO) Team: randomised controlled trial of the effectiveness of specialised care for early psychosis. BMJ 2004;329:1067-71. - PMC - PubMed
1. Sterne JA, Davey Smith G. Sifting the evidence—what’s wrong with significance tests? BMJ 2001;322:226-31. - PMC - PubMed
1. Henderson M, Wight D, Raab GM, Abraham C, Parkes A, Scott S, et al. Impact of a theoretically based sex education programme (SHARE) delivered by teachers on NHS registered conceptions and terminations: final results of cluster randomised trial. BMJ 2007;334:133-8. - PMC - PubMed

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[1] Kaptchuk TJ. Effect of interpretive bias on research evidence. BMJ 2003;326:1453-5. - PMC - PubMed

[2] Kaptchuk TJ. Effect of interpretive bias on research evidence. BMJ 2003;326:1453-5. - PMC - PubMed

[3] Meyer G, Warnke A, Bender R, Muhlhauser I. Effect on hip fractures of increased use of hip protectors in nursing homes: cluster randomised controlled trial. BMJ 2003;326:76-80. - PMC - PubMed

[4] Meyer G, Warnke A, Bender R, Muhlhauser I. Effect on hip fractures of increased use of hip protectors in nursing homes: cluster randomised controlled trial. BMJ 2003;326:76-80. - PMC - PubMed

[5] Craig TKJ, Garety P, Power P, Rahaman N, Colbert S, Fornells-Ambrojo M, et al. The Lambeth Early Onset (LEO) Team: randomised controlled trial of the effectiveness of specialised care for early psychosis. BMJ 2004;329:1067-71. - PMC - PubMed

[6] Craig TKJ, Garety P, Power P, Rahaman N, Colbert S, Fornells-Ambrojo M, et al. The Lambeth Early Onset (LEO) Team: randomised controlled trial of the effectiveness of specialised care for early psychosis. BMJ 2004;329:1067-71. - PMC - PubMed

[7] Sterne JA, Davey Smith G. Sifting the evidence—what’s wrong with significance tests? BMJ 2001;322:226-31. - PMC - PubMed

[8] Sterne JA, Davey Smith G. Sifting the evidence—what’s wrong with significance tests? BMJ 2001;322:226-31. - PMC - PubMed

[9] Henderson M, Wight D, Raab GM, Abraham C, Parkes A, Scott S, et al. Impact of a theoretically based sex education programme (SHARE) delivered by teachers on NHS registered conceptions and terminations: final results of cluster randomised trial. BMJ 2007;334:133-8. - PMC - PubMed

[10] Henderson M, Wight D, Raab GM, Abraham C, Parkes A, Scott S, et al. Impact of a theoretically based sex education programme (SHARE) delivered by teachers on NHS registered conceptions and terminations: final results of cluster randomised trial. BMJ 2007;334:133-8. - PMC - PubMed

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Listen to the data when results are not significant

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Listen to the data when results are not significant

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