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. 2008 Jan;10(1):7-11.
doi: 10.1111/j.1524-6175.2007.07227.x.

At the tipping point: accomplishing population-wide sodium reduction in the United States

At the tipping point: accomplishing population-wide sodium reduction in the United States

Lawrence J Appel. J Clin Hypertens (Greenwich). 2008 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Mean pre‐ and post‐levels of urinary sodium excretion (a proxy of sodium intake) in 3 trials that tested interventions that focused only on salt reduction (left panel). 9, 13, 20 Mean pre‐ and post‐levels of urinary sodium excretion in 2 trials that combined sodium (Na) reduction with other lifestyle interventions (right panel). Trials of Hypertension Prevention, Phase 2 (TOHP2) tested an intervention combining sodium reduction with weight loss. 9 PREMIER tested a comprehensive intervention combining sodium reduction with weight loss, increased physical activity, and adoption of the Dietary Approaches to Stop Hypertension (DASH) diet. 21 TOHP1 indicates Trials of Hypertension Prevention, Phase 1; TONE, Trials of Nonpharmacologic Interventions in the Elderly.
Figure 2
Figure 2
Mean blood pressure (BP) in US children aged 1 to 17 years (left) 25 and mean BP in Yanomami adults aged 20 to 59 years. 26 Mean BP in US children is for those at 50th percentile of height.

References

    1. He FJ, MacGregor GA. Effect of modest salt reduction on blood pressure: A meta‐analysis of randomized trials. implications for public health. J Hum Hypertens. 2002;16:761–770. - PubMed
    1. Johnson AG, Nguyen TV, Davis D. Blood pressure is linked to salt intake and modulated by the angiotensinogen gene in normotensive and hypertensive elderly subjects. J Hypertens. 2001;19:1053–1060. - PubMed
    1. Sacks FM, Svetkey LP, Vollmer WM, et al. Effects on blood pressure of reduced dietary sodium and the dietary approaches to stop hypertension (DASH) diet. DASH‐sodium collaborative research group . N Engl J Med. 2001;344:3–10. - PubMed
    1. Weinberger MH, Miller JZ, Luft FC, et al. Definitions and characteristics of sodium sensitivity and blood pressure resistance. Hypertension. 1986;8:II127–II134. - PubMed
    1. Obarzanek E, Proschan MA, Vollmer WM, et al. Individual blood pressure responses to changes in salt intake: Results from the DASH‐sodium trial. Hypertension. 2003;42:459–467. - PubMed

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