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Case Reports
. 2007 Jul;17(4):265-8.
doi: 10.1055/s-2007-985195.

Clival pituitary adenoma with acromegaly: case report and review of literature

Harjinder S Bhatoe  1 , Narendra Kotwal, Sonia Badwal
Affiliations
Case Reports

Clival pituitary adenoma with acromegaly: case report and review of literature

Harjinder S Bhatoe et al. Skull Base. 2007 Jul.

Abstract

The pituitary develops as a result of complex, intricate, and precise neuro-embryological events in the sixth to eighth weeks of gestation. Some ectopic cell rests can become adenomatous. Rarely, these cell rests in the clivus can be the site of formation of adenoma. Our patient, a 35-year-old parous woman, was being treated for acromegaly, and imaging studies revealed a clival mass lesion. Trans-sphenoidal excision was done and immunohistochemistry revealed the tumor to be a growth hormone-secreting tumor.

Keywords: Acromegaly; clivus; pituitary tumor.

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Figures

Figure 1
Figure 1
Skull radiograph (lateral view) showing normal-sized sella with erosion of the floor.
Figure 2
Figure 2
MRI (T1-weighted, gadolinium enhanced) showing intraclival tumor.
Figure 3
Figure 3
Photo micrograph showing uniform round to oval tumor cells in a sinusoidal pattern. (hematoxylin and eosin, × 200.)
See this image and copyright information in PMC

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