Clival pituitary adenoma with acromegaly: case report and review of literature
- PMID: 18174927
- PMCID: PMC2039716
- DOI: 10.1055/s-2007-985195
Clival pituitary adenoma with acromegaly: case report and review of literature
Abstract
The pituitary develops as a result of complex, intricate, and precise neuro-embryological events in the sixth to eighth weeks of gestation. Some ectopic cell rests can become adenomatous. Rarely, these cell rests in the clivus can be the site of formation of adenoma. Our patient, a 35-year-old parous woman, was being treated for acromegaly, and imaging studies revealed a clival mass lesion. Trans-sphenoidal excision was done and immunohistochemistry revealed the tumor to be a growth hormone-secreting tumor.
Keywords: Acromegaly; clivus; pituitary tumor.
Figures
References
-
- Erdheim J. Über einen Hypophysentumor von ungewöhnlichem. Sitz Beitr Pathol Anat. 1909;46:233–240.
-
- De Witte O, Massager N, Salmon I, Meyer S, Dooms G, Brotchi J. Ectopic prolactinoma in the clivus. Acta Chir Belg. 1998;98:10–13. - PubMed
-
- Hori A, Schmidt D, Rickels E. Pharyngeal pituitary: development, malformation and tumorigenesis. Acta Neuropathol (Berl) 1999;98:262–272. - PubMed
-
- McGrath P. Extrasellar adenohypophyseal tissue in the female. Australas Radiol. 1970;14:241–247. - PubMed
-
- Anand V K, Osborne M, Harkey H L. Infiltrative clival pituitary adenoma of ectopic origin. Otolaryngol Head Neck Surg. 1993;108:178–183. - PubMed