Evidence for a complex interaction between HLA-DRB1 and environmental factors in MS

Editorial

Bertrand Fontaine et al. Neurology. 2008.

. 2008 Jan 8;70(2):97-8.

doi: 10.1212/01.wnl.0000296821.72466.d3.

No abstract available

Comment on

HLA-DRB1 and multiple sclerosis in Malta.
Dean G, Yeo TW, Goris A, Taylor CJ, Goodman RS, Elian M, Galea-Debono A, Aquilina A, Felice A, Vella M, Sawcer S, Compston DA. Dean G, et al. Neurology. 2008 Jan 8;70(2):101-5. doi: 10.1212/01.wnl.0000284598.98525.d7. Epub 2007 Dec 5. Neurology. 2008. PMID: 18057318

Protective role of the HLA-A*02 allele in Portuguese patients with multiple sclerosis.
Silva AM, Bettencourt A, Pereira C, Santos E, Carvalho C, Mendonça D, Costa PP, Monteiro L, Martins B. Silva AM, et al. Mult Scler. 2009 Jun;15(6):771-4. doi: 10.1177/1352458509104588. Mult Scler. 2009. PMID: 19482867
HLA-DRB1*15, low infant sibling exposure, and multiple sclerosis gene-environment interaction.
Ramagopalan SV, Dyment DA, Giovannoni G, Sadovnick AD, Ebers GC. Ramagopalan SV, et al. Ann Neurol. 2010 May;67(5):694-5. doi: 10.1002/ana.21900. Ann Neurol. 2010. PMID: 20437569 No abstract available.
Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex.
Chao MJ, Ramagopalan SV, Herrera BM, Lincoln MR, Dyment DA, Sadovnick AD, Ebers GC. Chao MJ, et al. Hum Mol Genet. 2009 Jan 15;18(2):261-6. doi: 10.1093/hmg/ddn353. Hum Mol Genet. 2009. PMID: 19098025
The role of vitamin D in multiple sclerosis.
Kampman MT, Steffensen LH. Kampman MT, et al. J Photochem Photobiol B. 2010 Nov 3;101(2):137-41. doi: 10.1016/j.jphotobiol.2010.04.003. Epub 2010 Apr 21. J Photochem Photobiol B. 2010. PMID: 20471852 Review.
An overview of gene-epigenetic-environmental contributions to MS causation.
Lincoln JA, Cook SD. Lincoln JA, et al. J Neurol Sci. 2009 Nov 15;286(1-2):54-7. doi: 10.1016/j.jns.2009.06.037. Epub 2009 Jul 19. J Neurol Sci. 2009. PMID: 19616791 Review.

Epigenetic principles and mechanisms underlying nervous system functions in health and disease.
Mehler MF. Mehler MF. Prog Neurobiol. 2008 Dec 11;86(4):305-41. doi: 10.1016/j.pneurobio.2008.10.001. Epub 2008 Oct 17. Prog Neurobiol. 2008. PMID: 18940229 Free PMC article. Review.