Review
doi: 10.1016/j.ghir.2007.11.004.
Epub 2008 Jan 7.
Idiopathic short stature: definition, epidemiology, and diagnostic evaluation
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- PMID: 18182313
- DOI: 10.1016/j.ghir.2007.11.004
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Review
Idiopathic short stature: definition, epidemiology, and diagnostic evaluation
Growth Horm IGF Res.
2008 Apr.
Abstract
Idiopathic short stature is a condition in which the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex and population, in whom no identifiable disorder is present. It can be subcategorized into familial and non-familial ISS, and according to pubertal delay. It should be differentiated from dysmorphic syndromes, skeletal dysplasias, short stature secondary to a small birth size (small for gestational age, SGA), and systemic and endocrine diseases. ISS is the diagnostic group that remains after excluding known conditions in short children.
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