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Review
. 2008 Jul;37(6):721-8.
doi: 10.1007/s00249-007-0256-x. Epub 2008 Jan 9.

Mechanisms of protein folding

Ylva Ivarsson  1 , Carlo Travaglini-Allocatelli, Maurizio Brunori, Stefano Gianni
Affiliations
Review

Mechanisms of protein folding

Ylva Ivarsson et al. Eur Biophys J. 2008 Jul.

Abstract

Understanding the mechanism by which a polypeptide chain folds into its native structure is a central problem of modern biophysics. The collaborative efforts of experimental and theoretical studies recently raised the tantalizing possibility to define a unifying mechanism for protein folding. In this review we summarize some of these intriguing advances and analyze them together with a discussion on the new findings concerning the so-called downhill folding.

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