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Comment
. 2008 Mar 1;586(5):1209-11.
doi: 10.1113/jphysiol.2007.149484. Epub 2008 Jan 10.

The ups and downs of assessing baroreflex function

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The ups and downs of assessing baroreflex function

Colin N Young et al. J Physiol. .
No abstract available

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Figures

Figure 1
Figure 1. Analysis of overall baroreflex gain alone may mask an impaired ability to respond to hypotension
This figure illustrates an impaired cardiac response to a nitroprusside (NTP)-induced hypotensive challenge in a diabetic patient compared with a control subject whereas the response to a phenylephrine (PE)-induced hypertensive challenge is similar. In this example, consideration of overall integrated baroreflex gain alone (inset) would lead to impairments in baroreflex regulation of blood pressure being overlooked. This illustrates the importance of separately examining the cardiac responses to falls and rises in blood pressure in order to fully assess baroreflex function using the modified Oxford technique.

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