Cellular transformation in vitro induced by herpes simplex virus (HSV). Note III. Oncogenicity of some HSV-2-transformed cell lines
- PMID: 181902
Cellular transformation in vitro induced by herpes simplex virus (HSV). Note III. Oncogenicity of some HSV-2-transformed cell lines
Abstract
At high in vitro passage levels HSV-2-transformed hamster and rat cell lines were oncogenic for the homologous animals, inducing fusocellular or round-cell sarcomas. The cell lines obtained by in vitro cultivation of the tumors were free of infectious virus.
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