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. 1976 Jan-Mar;27(1):47-50.

Cellular transformation in vitro induced by herpes simplex virus (HSV). Note III. Oncogenicity of some HSV-2-transformed cell lines

N Sahnazarov, A Muţiu, M Gruia, C Surdan, C Cernescu, R Gologan, N Cajal
  • PMID: 181902

Cellular transformation in vitro induced by herpes simplex virus (HSV). Note III. Oncogenicity of some HSV-2-transformed cell lines

N Sahnazarov et al. Virologie. 1976 Jan-Mar.

Abstract

At high in vitro passage levels HSV-2-transformed hamster and rat cell lines were oncogenic for the homologous animals, inducing fusocellular or round-cell sarcomas. The cell lines obtained by in vitro cultivation of the tumors were free of infectious virus.

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