Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 May:28 Suppl 1:S67-72.
doi: 10.1007/s10875-007-9160-5. Epub 2008 Jan 12.

Inflammatory manifestations in chronic granulomatous disease (CGD)

S D Rosenzweig  1
Affiliations
Review

Inflammatory manifestations in chronic granulomatous disease (CGD)

S D Rosenzweig. J Clin Immunol. 2008 May.

Abstract

Chronic granulomatous disease (CGD) is a genetically heterogeneous disease characterized by recurrent life-threatening infections with bacteria and fungi as well as dysregulated inflammatory mechanisms. CGD is caused by defects in the NADPH oxidase, the enzyme complex responsible for generation of superoxide and other reactive oxygen species (ROS) in phagocytic cells. In this review we will focus our attention on those particular inflammatory manifestations associated with CGD, their frequencies and the underlying immunologic mechanisms favoring it occurrence.

PubMed Disclaimer

References

    1. J Urol. 1992 May;147(5):1314-8 - PubMed
    1. Int Rev Immunol. 1998;17(1-4):217-28 - PubMed
    1. Pediatr Infect Dis J. 2004 Sep;23 (9):882-4 - PubMed
    1. Eur J Immunol. 2007 Apr;37(4):1087-96 - PubMed
    1. J Leukoc Biol. 2003 May;73(5):591-9 - PubMed

Publication types

LinkOut - more resources