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Comment
. 2008 Jan;14(1):4-6.
doi: 10.1016/j.devcel.2007.12.014.

Retromer retrieves wntless

Suzanne Eaton  1
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Free article
Comment

Retromer retrieves wntless

Suzanne Eaton. Dev Cell. 2008 Jan.
Free article

Abstract

Wntless is a sorting receptor required for Wnt secretion. Wntless is retrieved from endosomes to the Golgi by retromer, permitting Wntless reutilization in Wnt transport. In the absence of retromer, Wntless is degraded in lysosomes and Wnt secretion is impaired.

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