Review
doi: 10.1007/978-1-4684-0955-0_24.
Phospholipid-induced modifications in the brain of animals fed with cholesterol-supplemented diet
- PMID: 181962
- DOI: 10.1007/978-1-4684-0955-0_24
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Review
Phospholipid-induced modifications in the brain of animals fed with cholesterol-supplemented diet
Adv Exp Med Biol.
1976.
Abstract
1) Cholesterol - enriched diet induces changes in the phospholipid fatty acids of particulate fractions and modifications in the membrane-bound enzyme: 2) BC-PL (100 mg/kg i.p., as shown in rabbits) prevent cholesterol-induced modifications at brain level: 3)BC-PL (100 mg/kg i.v., as shown in mice) have a recovery effect on the cholesterol-induced modification at brain level; 4) It is suggested that some atherosclerotic lesions are analogous to those reproduced by anoxia; 5) It is suggested that the effect of BC-PL is a direct action at the level of the brain cellular membranes.