Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Feb;37(2):320-30.
doi: 10.1039/b610213c. Epub 2007 Dec 13.

Fluorine in medicinal chemistry

Sophie Purser  1 , Peter R Moore, Steve Swallow, Véronique Gouverneur
Affiliations
Review

Fluorine in medicinal chemistry

Sophie Purser et al. Chem Soc Rev. 2008 Feb.

Abstract

It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.

PubMed Disclaimer

Substances

LinkOut - more resources