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Comment
. 2008 Jan;28(1):8-10.
doi: 10.1016/j.immuni.2007.12.007.

Understanding lupus: fishing genes out of mice and men

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Understanding lupus: fishing genes out of mice and men

Tim J Vyse. Immunity. 2008 Jan.
Free article

Abstract

In this issue of Immunity, the Coronin-1A gene Coro1a, which regulates cytoskeletal structure, is shown by Haraldsson et al. (2007) to be a surprising disease-susceptibility gene that contributes to the spontaneous systemic autoimmunity in the MRL mouse, a model of systemic lupus erythematosus.

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