Monster protein controls calcium entry and fights infection
- PMID: 18199413
- DOI: 10.1016/j.immuni.2007.12.009
Monster protein controls calcium entry and fights infection
Abstract
Sustained calcium signaling in T cells is critical for development and activation. In this issue of Immunity, Matza et al. (2007) demonstrate that the huge scaffold protein, AHNAK1, interacts with L-type calcium channels, regulates Ca2+ influx, and defends against Leishmania major infection.
Comment on
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A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation.Immunity. 2008 Jan;28(1):64-74. doi: 10.1016/j.immuni.2007.11.020. Immunity. 2008. PMID: 18191595 Free PMC article.
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